By M. Tubiana (auth.), Professor Georges Mathé, Professor Maxime Seligmann, Dr. Maurice Tubiana (eds.)
We have studied 24 situations of secondarily leukemic (stage V) lymphosarcoma (LS), 31 instances of "d'emblee" leukemic LS, and ten instances of lymphoid leukemic neoplasias transitional among "d'emblee" leukemic LS and persistent lymphocytic leukemia (eLL). those circumstances simply main issue the typical forms ofthe WHO type ofLS, i.e., the prolymphocytic, the lymphoblastic, and the immunoblastic. a few situations have additionally been categorised through cellphone floor markers. The secondarily leukemic conversion happened in forty% of the lymphoblastic forms, in 14% of the prolymphocytic kinds, and in 17% of the immunoblastic kinds. It by no means happened at degree I yet may well take place after the other degree. The mediastinal involvement was once saw in 3 varieties, yet traditionally within the lymphoblastic sort. The analysis after an acute lymphoid leukemia (ALL) therapy comprising energetic immunotherapy following chemo(radio)therapy is best for the leukemic prolymphocytic and lymphoblastic LS than for the immunoblastic variety. sufferers (one of the lymphoblastic style) are in entire remission after eight and five years, respectively. we now have defined ten circumstances of "d'emblee" leukemic LS with both huge lymphoid or additional lymphoid lots, bone marrow leukemic telephone involvement, and LS points of neoplastic cells. Mediastinal, stomach, or different tumor plenty are frequent.
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