By John L. Wallace (auth.), Timothy S. Gaginella, Antonio Guglietta (eds.)
Drug improvement: Molecular pursuits for Gastrointestinal sickness brings jointly a panel of wonderful specialists to severely overview the various promising new parts of gastrointestinal pharmacology on the molecular point. Key chapters speak about such significant topics because the cyclooxygenase-2 inhibitors, the complexities of nitric oxide pathways within the intestine, and the effect of cytokines on inflammatory bowel disorder, in addition to new possibilities for pharmacotherapy, together with peptide development elements, tachykinins-particularly substance P and neurokinins-cholecystokinin receptors, and serotonin. additionally tested as attainable websites for treating motility issues and visceral soreness are the opioid receptors dwelling within the intestine, and the H3-receptor agonists for treating intestine irritation and discomfort. Drug improvement: Molecular ambitions for Gastrointestinal sickness offers a entire assessment of state-of-the-art molecular pharmacological techniques to the invention and improvement of novel medicinal drugs for gastrointestinal and liver illnesses. Its broad references, richly skilled members, and state-of-the-art syntheses of previous, current, and emergent learn identify the e-book as an important source for all pharmacologists, medicinal chemists, and clinicians looking extra strong medicinal drugs for the prevention and remedy of gastrointestinal issues.
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